THE WOBBLER MOUSE MODEL OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) DISPLAYS HIPPOCAMPAL HYPEREXCITABILITY, AND REDUCED NUMBER OF INTERNEURONS, BUT NO PRESYNAPTIC VESICLE RELEASE IMPAIRMENTS.

The Wobbler mouse model of amyotrophic lateral sclerosis (ALS) displays hippocampal hyperexcitability, and reduced number of interneurons, but no presynaptic vesicle release impairments.

Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease.It is a fatal degenerative disease, best recognized for its debilitating neuromuscular effects.ALS however also induces cognitive impairments in as many as 50% of affected individuals.Moreover, many ALS patients demonstrate cortical hyperexcitability, which has

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Pulse oximeter ingestion in a psychotic patient

Psychotic conditions such as schizophrenia, bipolar disorder, major depressive disorder, and polysusbstance abuse are Suspension Lift Kit risk factors for foreign body ingestion.A foreign body can include sharp objects that lead to serious complications.In this case report, we present a patient with a history of psychosis who ingested a pulse oxime

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